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The cardiomyopathies: Hypertrophic, dilated, restrictive, and right ventricular 

The cardiomyopathies: Hypertrophic, dilated, restrictive, and right ventricular
Chapter:
The cardiomyopathies: Hypertrophic, dilated, restrictive, and right ventricular
Author(s):

Oliver P. Guttmann

, and Perry Elliott

DOI:
10.1093/med/9780198746690.003.0354
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date: 25 February 2021

The term cardiomyopathy is used to describe heart muscle disease unexplained by abnormal loading conditions (hypertension, valve disease, and others), congenital cardiac abnormalities, and ischaemic heart disease. The current classification is based on the predominant phenotype, that is, hypertrophic, dilated, arrhythmogenic right ventricular, restrictive, and unclassifiable (including left ventricular non-compaction), and— where possible— incorporating inheritance and genotype. The diagnosis of hypertrophic cardiomyopathy is based on the demonstration of unexplained myocardial hypertrophy, defined as a wall thickness measurement exceeding two standard deviations above normal for gender and age. In practice, in an adult of normal size, the presence of a left ventricular myocardial segment of 1.5 cm or greater in thickness is diagnostic. Less stringent criteria should be applied to first-degree relatives of an unequivocally affected individual.

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