Show Summary Details
Page of

Cytokines 

Cytokines
Chapter:
Cytokines
Author(s):

Iain B. McInnes

DOI:
10.1093/med/9780198746690.003.0031
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2021. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 27 February 2021

74Cytokines are small glycoprotein mediators that are involved in every facet of immune effector function and regulation, and moreover serve to integrate immune function with other physiologic processes (e.g. metabolism, neurologic function). More than 200 cytokines have been identified. Understanding of the cytokine network has increasing importance in clinical practice with the advent of therapeutic strategies that target particular cytokines with exquisite specificity using biological agents, leading to remarkable advances in the treatment of inflammatory disorders (e.g. anti-TNF therapy in rheumatoid arthritis and anti-IL-17A in psoriasis). The therapeutic potential in their manipulation has not yet been maximized and the future will hold remarkable advances as these molecular networks give up their secrets to provide for highly specific and well-tolerated interventions.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.