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Hormonal manifestations of nonendocrine disease 

Hormonal manifestations of nonendocrine disease
Chapter:
Hormonal manifestations of nonendocrine disease
Author(s):

Thomas M. Barber

, and John A.H. Wass

DOI:
10.1093/med/9780198746690.003.0261
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date: 27 February 2021

Tumours (usually but not invariably malignant), other ‘non-endocrine conditions’ and drugs can be associated with a wide variety of endocrine syndromes. ‘Ectopic’ hormone secretion, defined as the release of a hormone from a site different from the gland that normally produces it, has classically been recognized in the context of neoplasia, but it is now apparent that many hormones are synthesized by ‘non-endocrine’ tissue. Although a particular endocrinopathy may be associated with a specific type of tumour in a particular organ, the relationship is not invariable, and many neoplasms elaborate more than one hormonal substance at the same or at different times and thus produce a mixed endocrine picture.

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