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Lymphatic filariasis 

Lymphatic filariasis
Chapter:
Lymphatic filariasis
Author(s):

Richard Knight

DOI:
10.1093/med/9780198746690.003.0174
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date: 25 February 2021

Wuchereria bancrofti, Brugia malayi, and B. timori are mosquito-borne lymphatic-dwelling nematode parasites that are important causes of morbidity, disability, and social stigma in tropical and subtropical countries. The total population at risk is now estimated to be 856 million in some 52 countries where these infections are endemic. In 2000 before systematic control programmes 120 million people were infected, of whom about 40 million had clinical disease and some 80 million had hidden lymphatic damage. Bancroftian filariasis due to W. bancrofti, which has no animal reservoir, accounts for 90% human infections worldwide; it was introduced into the Americas from Africa by the Atlantic slave trade.

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