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Endocrine and metabolic complications of advanced cancer 

Endocrine and metabolic complications of advanced cancer
Endocrine and metabolic complications of advanced cancer

Max Watson

, Rachel Campbell

, Nandini Vallath

, Stephen Ward

, and Jo Wells

Page of

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date: 22 August 2019

This chapter covers the common endocrine and metabolic complications associated with malignancies such as hypercalcaemia, SIADH, and changes in glucose metabolism. It also outlines a strategy for managing the patient with iatrogenic hyperglycaemia as well as the patient with diabetes mellitus in the last phase of life. Metabolic and endocrinological disorders have a profound impact on a patient’s physical and psychological well-being. These disorders are at times complex, but it is important to be aware of the associated endocrine and metabolic complications in advanced cancer as they can have a significant impact on morbidity and mortality. In addition, even when the underlying cancer may not be responsive to treatment, such symptoms may be reversible, which can have a significant benefit to the individual patient.

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