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Endomyocardial biopsy in the failing heart 

Endomyocardial biopsy in the failing heart
Endomyocardial biopsy in the failing heart

Michael J. Domanski

, Mark Halushka

, and Sean P. Pinney

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date: 12 July 2020

Endomyocardial biopsy enables direct microscopic examination of the myocardium. Clinical application is generally categorized by surveillance for rejection of a transplanted heart and diagnosis of cardiomyopathy including supporting chemotherapy decisions when direct examination of tissue provides risk assessment not otherwise available. This chapter begins with a discussion of the diagnosis of cardiomyopathies, referencing various scenarios taken from recent guidelines seeking to clarify the role of endomyocardial biopsy in routine cardiology practice. This is followed by a discussion of endomyocardial biopsy for rejection surveillance after cardiac transplantation, and a review of technical aspects.

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