Show Summary Details
Page of

Complications after cardiac transplantation 

Complications after cardiac transplantation
Chapter:
Complications after cardiac transplantation
Author(s):

Howard J. Eisen

DOI:
10.1093/med/9780198734871.003.0019
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2016. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 22 September 2019

Cardiac transplantation represents definitive therapy for selected patients who have exhausted other therapeutic options for heart failure and can provide both long-term survival and quality of life for these patients. Survival and quality of life after cardiac transplantation are limited by a number of adverse clinical events. The appearance of these is often dependent on the time after cardiac transplantation and they represent the consequences of the transplant procedure itself, the alloimmune responses to the transplanted heart, and the side effects of the immunosuppressive therapies used to blunt these responses. Early adverse events include acute cellular rejection and infections. Later complications include cardiac allograft vasculopathy, malignancies, and antibody-mediated rejection. Adverse events related to the immunosuppressive therapy also occur. Adjustments in immunosuppressive regimens and implementation of diagnostic procedures and therapies may mitigate the impact of complications and improve outcomes.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.