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Advanced heart failure in perspective 

Advanced heart failure in perspective
Advanced heart failure in perspective

Marc A. Pfeffer

, Michael J. Domanski

, and Mandeep R. Mehra

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date: 13 July 2020

Heart failure is a wide-ranging clinical syndrome broadly categorized by the inability of the heart to maintain adequate pump function without utilizing reserve mechanisms. This chapter briefly covers the multitude of abnormalities that distort cardiac performance both symptomatically and asymptomatically, demonstrating the complex nature of diagnosis and prognosis of heart failure. Using a range of clinical trials and relevant guidelines in order to explore the various stages and categories of heart failure, it defines the need for a distinct subspecialty of advanced heart failure and cardiac transplantation within the context of heart failure as a whole.

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