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Extra-articular manifestations: psoriasis 

Extra-articular manifestations: psoriasis
Chapter:
Extra-articular manifestations: psoriasis
Author(s):

Wolf-Henning Boehncke

and Dafna D. Gladman

DOI:
10.1093/med/9780198734444.003.0018
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date: 03 April 2020

Psoriasis is a chronic, recurrent inflammatory skin disease, affecting about 2% of the world’s population. In 2014, the World Health Organization’s member states adopted a resolution on psoriasis, recognizing it as ‘a chronic, non-communicable, painful, disfiguring, and disabling disease for which there is no cure’. The resolution acknowledges the psychosocial burden of the disease and that many people with psoriasis suffer due to lack of awareness and access to sufficient treatment. Psoriasis is a multifaceted disease including not only a variety of skin lesions, but also joint manifestations and comorbidities. This chapter focuses on the clinical features of psoriasis of the skin and its underlying pathogenesis, taking into account the current status of genetic research in the field. It also describes psoriatic arthritis, as well as the association of psoriasis with spondyloarthritis.

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