Show Summary Details
Page of

Mumps 

Chapter:
Mumps
DOI:
10.1093/med/9780198729228.003.0090
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2016. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 18 November 2019

Mumps is caused by a paramyxovirus that typically infects salivary glands but which can cause meningitis, orchitis, pancreatitis, and other clinical manifestations. The incubation period is 2–3 weeks. Although not highly contagious, the virus is excreted in saliva 2 days before symptoms and about 5 days afterwards, and does spread by respiratory secretions. Specific diagnosis can be made by polymerase chain reaction or virus isolation. Serologic methods are useful if acute and convalescent specimens are available, and demonstration of immunoglobulin M antibodies is helpful but insensitive. Neutralizing antibodies are considered protective, but strain variation makes definition of the level needed uncertain. Prophylaxis consists of vaccination with one or another live attenuated strains, usually in combination with measles and rubella live vaccines. Two doses are considered necessary as part of primary immunization, but immune memory is not as consistent as after measles and rubella vaccines, and therefore many outbreaks have occurred in vaccinated populations, often those in which individuals are in close contact. There is some evidence that a third dose will stop outbreaks in those populations. Only symptomatic treatment is available.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.