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Viral haemorrhagic fevers 

Viral haemorrhagic fevers
Chapter:
Viral haemorrhagic fevers
DOI:
10.1093/med/9780198729228.003.0070
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date: 19 November 2019

Hand, foot, and mouth disease (HFMD) is a common acute childhood viral disease.The commonest symptoms are fever, rash with vesicles or erosions in the oral mucosa, and rash (sometimes with blisters) on hands and feet. Hand, foot, and mouth disease is usually diagnosed clinically, but polymerase chain reaction or virus culture could be used for confirmation. Usually it is a mild and self-limiting disease, but complicated cases may occur. A prophylactic inactivated vaccine containing EV71 (Sinovac 781) has been recently approved in China. The aetiology, epidemiology, clinical features, diagnosis, differential diagnosis, management, and prevention of hand, foot, and mouth disease are described.

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