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Antiparasitics 

Antiparasitics
Chapter:
Antiparasitics
DOI:
10.1093/med/9780198729228.003.0003
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date: 26 June 2019

Use of antiviral therapy is key to the successful management of chronic, as well as many acute, viral infections. The development of direct-acting antivirals acting at different stages of viral replication cycles has revolutionized the way infections like HIV and hepatitis C are treated and has altered the prognosis for affected patients. This chapter provides a summary of the main categories of compounds available, their indications, mechanisms of action, and resistance patterns. The availability of antivirals for use in the paediatric population remains challenging, hampered by the availability of formulations suitable for use in children, as well as the need for robust safety data.

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