Show Summary Details
Page of

Typhus 

Chapter:
Typhus
DOI:
10.1093/med/9780198729228.003.0123
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2016. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 18 November 2019

Typhus is an acute and widespread infectious disease in the world. It is a member of rickettsiosis which is caused by intracellular bacteria, including Rickettsia typhi (causes murine or endemic typhus), Rickettsia prowazekii (causes epidemic typhus), and Orientia tsutsugamushi (causes scrub typhus). Most children infected with the diseases may have similar clinical manifestations of fever of unknown origin or prolonged fever, chills, liver function impairment, severe headache, rash, jaundice, myalgia, and pulmonary symptoms. Multiple organ involvement may occur in critical conditions or fetal cases. Misdiagnosis can be easily made; physicians should be highly suspicious in children who have had a travel history and exposure in endemic areas. Early and appropriate empirical antibiotics should be used to reduce severe complications or mortality. However, doxycycline-resistant strain of scrub typhus has been reported. There is no vaccine available currently. This chapter on typhus has been extensively revised and updated; current and clinical approaches to evaluating and managing typhus in children are studied. In addition, useful pictures of typical eschars and chiggers bites on bodies are also shown.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.