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Isolated ventricular non-compaction 

Isolated ventricular non-compaction
Isolated ventricular non-compaction

Frank Weidemann

, Gilbert Habib

, and Clara Vazquez

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date: 26 January 2022

Isolated ventricular non-compaction (IVNC) in adults is a rare congenital cardiomyopathy characterized by the presence of prominent myocardial trabeculations in the apical segments of the left ventricle with deep inter-trabecular recesses in communication with the ventricular cavity. Until now there is no clear genetic or laboratory test for the diagnosis of IVNC and thus the diagnosis is defined by clinical and imaging criteria. During echocardiography a maximal end-systolic ratio between the non-compacted endocardial layer and the compacted layer of greater than 2 is consistent with IVNC. This chapter focuses on the definition of IVNC and typical imaging features seen by standard and by advanced echocardiography.

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