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Miscellaneous drugs 

Miscellaneous drugs
Miscellaneous drugs

Carl Waldmann

, Andrew Rhodes

, Neil Soni

, and Jonathan Handy

Page of

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date: 24 January 2022

This chapter discusses miscellaneous drugs involved in critical care and includes antibiotics, involving discussion on antibiotic usage, classification and mechanism of action of antibiotics, context of antibiotic usage, key points for appropriate use of antibiotics, resistance issues, resistant organisms, and special considerations, including selective decontamination of the digestive tract, eubiosis and dysbiosis, and the future of antimicrobial therapy. This chapter also discusses antifungals, including amphotericin B, azoles, echinocandins, flucytosine, and important considerations regarding the use of antifungals in critically ill patients; antiviral agents, including acyclovir, ganciclovir, and valganciclovir, foscarnet, cidofovir, oseltamivir, and zanamivir; and N-acetylcysteine (modes of action, indications, dosing, and side-effects).

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