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Central nervous system 

Central nervous system
Central nervous system

Berenice C. Langdon

and Aodhán S. Breathnach

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date: 21 May 2022

This chapter focuses on three presentations of the central nervous system: bacterial meningitis, viral meningitis, and neurosyphilis. The associated key microbes, Neisseria meningitides, coxsackie viruses, and Treponema pallidum are discussed as well as which samples are needed. The taking of a CSF sample is described in particular, to give a feel of how this is done and the processing of CSF samples in the laboratory to check for bacteria and fungi is also dealt with as well as the more modern techniques of multiplex PCR for viral meningitis. The various stages of syphilis are described and the history of this interesting illness touched on as well as the relevant modern serological testing and treatment.

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