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The Irritative, Epileptogenic, and Ictal Onset Zones in Depth EEG 

The Irritative, Epileptogenic, and Ictal Onset Zones in Depth EEG
Chapter:
The Irritative, Epileptogenic, and Ictal Onset Zones in Depth EEG
Author(s):

Fabrice Bartolomei

DOI:
10.1093/med/9780198714668.003.0009
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date: 20 August 2019

‘Irritative, epileptogenic, and ictal onset zones in depth EEG’ reviews the three classical brain regions that are to be defined by epileptologists during invasive EEG recordings. It first reviews the concept of the epileptogenic zone (EZ) and the different historical definitions and then the patterns of ictal onset observed from depth EEG recordings. It then discusses the concept of irritative zone, which is related to the interictal spike distribution, and its relationship with the EZ. Finally, the concept of ‘epileptogenic networks’ is developed, offering a modern framework for the functional anatomy of focal epilepsies.

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