Show Summary Details
Page of

The Irritative Zone and Seizure Onset Zone in Subdural EEG 

The Irritative Zone and Seizure Onset Zone in Subdural EEG
Chapter:
The Irritative Zone and Seizure Onset Zone in Subdural EEG
Author(s):

Sebastian Bauer

, and Felix Rosenow

DOI:
10.1093/med/9780198714668.003.0008
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2016. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 23 October 2019

Subdural EEG has a high sensitivity for detecting interictal spikes. The irritative zone is usually more extended than the seizure onset zone. Removal of the entire irritative zone improves outcome in extratemporal as well as neocortical and tumour-related temporal lobe epilepsy, but not in mesial TLE. Quantification of spike features like amplitude, frequency, or latency may help differentiate the localizing and prognostic value of different spike populations. Although EEG patterns are not aetiology, some pathologies such as focal cortical dysplasias are frequently associated with typical EEG patterns, in which case intraoperative electrocorticography should be applied to tailor resections. Presence of a focal seizure onset zone and slow propagation are associated with good surgical outcome. Definition of a sound hypothesis about location of the seizure onset zone from pre-invasive findings is a crucial prerequisite for the success of subdural recordings. Concordance of interictal and ictal recordings is highly predictive of outcomes.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.