Show Summary Details
Page of

Simultaneous Macro- and Microrecordings 

Simultaneous Macro- and Microrecordings
Chapter:
Simultaneous Macro- and Microrecordings
Author(s):

Michal T. Kucewicz

, B. Michael Berry

, and Gregory A. Worrell

DOI:
10.1093/med/9780198714668.003.0036
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2016. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 17 August 2019

Invasive recordings from patients with epilepsy are increasingly employing new hybrid electrode technologies, which combine macro- and microelectrode electrophysiology, to explore the large scope of brain processes. These range from action potentials of single neurons to coordinated activity of neuronal ensembles to oscillations of widespread brain networks, all buried in oscillations of the extracellular local field potential sampled at various spatiotemporal scales. This chapter reviews various approaches to simultaneous micro- and macroscale electrophysiology, with current electrode designs and applications being discussed together with particular examples of epilepsy pathophysiology. The chapter highlights the advantages, limitations, and challenges for new technologies in the emerging era of human brain mapping projects. It is this technological advance that drives the progress of human intracranial electrophysiology and shifts attention to a vast scale of neuronal networks.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.