Show Summary Details
Page of

Invasive EEG and Hippocampal Sclerosis 

Invasive EEG and Hippocampal Sclerosis
Chapter:
Invasive EEG and Hippocampal Sclerosis
Author(s):

Jerome Engel

, Richard Staba

, and Itzhak Fried

DOI:
10.1093/med/9780198714668.003.0014
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2016. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 19 August 2019

Hippocampal sclerosis is the most common lesion associated with pharmacoresistant epilepsy, and anterior temporal lobe resection for hippocampal sclerosis remains the most common surgical treatment for epilepsy in adults. There are several different types of hippocampal sclerosis. Although the predominant causes of this condition are unknown, much is understood concerning the pathophysiology and anatomy of the neuronal networks most often constituting the epileptogenic region, the resection of which is necessary and sufficient to eliminate spontaneous epileptic seizures. Advances in neuroimaging, clinical neurophysiology, neurocognitive testing, and other diagnostic procedures now permit successful surgical treatment of intractable seizures with a standardized anteromesial temporal resection in most patients. Invasive monitoring is necessary in a minority of patients and is based on the known anatomy and pathophysiology of mesial temporal lobe epilepsy. A seizure-free outcome can be expected in 70–85% of patients.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.