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Amniotic fluid embolism (anaphylactoid syndrome of pregnancy) 

Amniotic fluid embolism (anaphylactoid syndrome of pregnancy)
Chapter:
Amniotic fluid embolism (anaphylactoid syndrome of pregnancy)
Author(s):

John A. Anderson

, Pierre-Antoine Laloë

, and Derek J. Tuffnell

DOI:
10.1093/med/9780198713333.003.0038
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date: 25 February 2020

Amniotic fluid embolus (AFE) is a rare occurrence but consistently remains one of the leading causes of maternal death in the developed world each year. Incidence in the United Kingdom is approximately 1 in 50,000 maternities and this seems to have stayed roughly stable. Quoted survival rates are improving, which may be a reflection of improved understanding and better care. This chapter aims to give an epidemiological background, outline the principles which are believed to underpin the pathophysiological changes which occur in episodes of AFE, and give readers a guide to treatment immediately following a maternal collapse due to AFE and ongoing supportive care thereafter.

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