Show Summary Details
Page of

Adjuvant drugs in neuraxial anaesthesia 

Adjuvant drugs in neuraxial anaesthesia
Adjuvant drugs in neuraxial anaesthesia

Catherine Cromey

and Susan Catling

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2020. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 01 December 2020

The addition of adjuvants to local anaesthetics for use in labour epidurals or for intrathecal administration is common practice in obstetric anaesthesia. This chapter provides an overview of the pharmacology of receptors within the epidural and intrathecal spaces and discusses the options available. Adjuncts are classified as opioid and non-opioid and each agent is explored in detail. The mechanism of action, clinical uses, effective dose ranges, speeds of onset and duration, side effects, disadvantages, and special circumstances associated with each agent are explored. Where formal guidelines exist, these are discussed in detail. Although large randomized controlled trial data is lacking, information regarding current knowledge of the behaviour of these agents in obstetric and non-obstetric practice is presented to assist clinicians when deciding about the appropriateness of each agent for their individual practice.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.