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Healthcare-associated infections and emergence of antibiotic resistance 

Healthcare-associated infections and emergence of antibiotic resistance
Healthcare-associated infections and emergence of antibiotic resistance

Benedikt Huttner

and Stephan Harbarth

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date: 16 May 2022

Healthcare-associated infections (HAI) present a significant challenge to the safe delivery of healthcare. The pool of patients at increased risk for HAI—such as chronically ill and immunosuppressed individuals—has been steadily growing due to the ageing of the population and advances in medicine. At the same time, pathogens resistant to multiple antimicrobials have become increasingly prevalent, complicating the management of HAI and increasing their associated morbidity and mortality. Older people are especially affected by these trends. Limitation of the use of invasive devices, preventing transmission through hand hygiene and other measures, and the appropriate use of antimicrobials for treatment and prophylaxis have all been recognized as key strategies for the control of HAI and antimicrobial resistance.

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