- Section 1 Ageing population and policy
- Section 2 Key concepts in care of older adults
- Section 3 Principles and organization of care
- Section 4 Age-related biological changes, altered physiology, and vulnerability to diseases and chronic conditions
- Section 5 Geriatric syndromes in clinical practice
- Section 6 Nutrition and metabolism
- Section 7 Mobility disorders: prevention, impact, and compensation
- Section 8 Infections in older adults: epidemiology, pathophysiology, diagnosis, and management
- Chapter 79 Immunosenescence and infectious diseases
- Chapter 80 Epidemiology of infection in elderly populations in various settings
- Chapter 81 Pneumonia and respiratory tract infections
- Chapter 82 Tuberculosis in old age
- Chapter 83 Bone and periprosthetic joint infections in older adults
- Chapter 84 Infective endocarditis
- Chapter 85 Ageing with HIV
- Chapter 86 Healthcare-associated infections and emergence of antibiotic resistance
- Chapter 87 Healthcare-associated infections and infection control
- Chapter 88 Vaccines against viral infections
- Chapter 89 Integration of vaccination of older adults in a life course programme
- Section 9 Cancer: epidemiology, pathophysiology, diagnosis, and management
- Section 10 Vascular diseases: epidemiology, pathophysiology, diagnosis, and management
- Section 11 Neurological disorders: epidemiology, pathophysiology, diagnosis, and management
- Section 12 Cognitive decline and dementia in older adults: epidemiology, pathophysiology, diagnosis, and management
- Section 13 Mental health of older adults
- Section 14 Management of common medical conditions: epidemiology, pathophysiology, diagnosis, and management
- Section 15 Palliative medicine and end-of-life care
- Section 16 Healthy ageing
(p. 629) Tuberculosis in old age
- Chapter:
- (p. 629) Tuberculosis in old age
- Author(s):
Aparajit Ballav Dey
and Ramesh Kandel
- DOI:
- 10.1093/med/9780198701590.003.0082
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. It is a common cause of death in the developing world among older persons. HIV/AIDS pandemic has led to rise in TB cases, development of drug resistance, and higher incidence of extrapulmonary disease. TB in old age can result from acquisition of new infection or reactivation of latent infection and progression to disease due to immunosenescence. It is a multisystem infection affecting virtually every organ system in the body, though pulmonary TB is the commonest manifestation. TB presents atypically in old age. The gold standard for diagnosis is isolation of the infective organism in culture, which is often difficult to achieve. The diagnostic strategies have improved with newer techniques based on nucleic acid amplification. Older patients have a higher risk of adverse drug reaction and poor treatment outcome. Control of TB requires efficiency in early detection and completion of treatment.
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- Section 1 Ageing population and policy
- Section 2 Key concepts in care of older adults
- Section 3 Principles and organization of care
- Section 4 Age-related biological changes, altered physiology, and vulnerability to diseases and chronic conditions
- Section 5 Geriatric syndromes in clinical practice
- Section 6 Nutrition and metabolism
- Section 7 Mobility disorders: prevention, impact, and compensation
- Section 8 Infections in older adults: epidemiology, pathophysiology, diagnosis, and management
- Chapter 79 Immunosenescence and infectious diseases
- Chapter 80 Epidemiology of infection in elderly populations in various settings
- Chapter 81 Pneumonia and respiratory tract infections
- Chapter 82 Tuberculosis in old age
- Chapter 83 Bone and periprosthetic joint infections in older adults
- Chapter 84 Infective endocarditis
- Chapter 85 Ageing with HIV
- Chapter 86 Healthcare-associated infections and emergence of antibiotic resistance
- Chapter 87 Healthcare-associated infections and infection control
- Chapter 88 Vaccines against viral infections
- Chapter 89 Integration of vaccination of older adults in a life course programme
- Section 9 Cancer: epidemiology, pathophysiology, diagnosis, and management
- Section 10 Vascular diseases: epidemiology, pathophysiology, diagnosis, and management
- Section 11 Neurological disorders: epidemiology, pathophysiology, diagnosis, and management
- Section 12 Cognitive decline and dementia in older adults: epidemiology, pathophysiology, diagnosis, and management
- Section 13 Mental health of older adults
- Section 14 Management of common medical conditions: epidemiology, pathophysiology, diagnosis, and management
- Section 15 Palliative medicine and end-of-life care
- Section 16 Healthy ageing