- Section 1 Ageing population and policy
- Section 2 Key concepts in care of older adults
- Section 3 Principles and organization of care
- Section 4 Age-related biological changes, altered physiology, and vulnerability to diseases and chronic conditions
- Section 5 Geriatric syndromes in clinical practice
- Section 6 Nutrition and metabolism
- Section 7 Mobility disorders: prevention, impact, and compensation
- Chapter 67 Gait disorders
- Chapter 68 Osteoporosis in the oldest old
- Chapter 69 Common fractures in older adults
- Chapter 70 Management of common fractures in older adults
- Chapter 71 Secondary prevention of fragility fractures
- Chapter 72 Osteoarthritis
- Chapter 73 Low back pain in older adults
- Chapter 74 Vasculitides in older people
- Chapter 75 Management of common types of arthritis in older adults
- Chapter 76 Foot problems
- Chapter 77 Injuries in sports activities in older people
- Chapter 78 Orthogeriatrics
- Section 8 Infections in older adults: epidemiology, pathophysiology, diagnosis, and management
- Section 9 Cancer: epidemiology, pathophysiology, diagnosis, and management
- Section 10 Vascular diseases: epidemiology, pathophysiology, diagnosis, and management
- Section 11 Neurological disorders: epidemiology, pathophysiology, diagnosis, and management
- Section 12 Cognitive decline and dementia in older adults: epidemiology, pathophysiology, diagnosis, and management
- Section 13 Mental health of older adults
- Section 14 Management of common medical conditions: epidemiology, pathophysiology, diagnosis, and management
- Section 15 Palliative medicine and end-of-life care
- Section 16 Healthy ageing
(p. 571) Vasculitides in older people
- Chapter:
- (p. 571) Vasculitides in older people
- Author(s):
Alexis Régent
and Loïc Guillevin
- DOI:
- 10.1093/med/9780198701590.003.0074
Vasculitides are a heterogeneous group of diseases, defined by vessel inflammation with fibrinoid necrosis of the arterial wall, giant-cell infiltration, and/or granuloma. Patients with giant cell arteritis (GCA) often have headaches, polymyalgia rheumatica, and vision symptoms in a context of moderately impaired health. Microscopic polyangiitis symptoms are very diverse, including alveolar haemorrhage, rapidly progressive glomerulonephritis, skin ulcers, mononeuritis multiplex, muscle, and joint pain. Other vasculitides, such as granulomatosis with polyangiitis (Wegener’s) (GPA) or cryoglobulinemic vasculitis occur less frequently in older patients. Diagnoses are based on clinical manifestations, laboratory results, imaging findings, and the established classification of vasculitides according to vessel size and histological findings. The treatment regimen, based on glucocorticoids and immunosuppressants, is chosen according to diagnosis and predictable outcome, and adapted to the patient’s age and concomitant comorbidities.
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- Section 1 Ageing population and policy
- Section 2 Key concepts in care of older adults
- Section 3 Principles and organization of care
- Section 4 Age-related biological changes, altered physiology, and vulnerability to diseases and chronic conditions
- Section 5 Geriatric syndromes in clinical practice
- Section 6 Nutrition and metabolism
- Section 7 Mobility disorders: prevention, impact, and compensation
- Chapter 67 Gait disorders
- Chapter 68 Osteoporosis in the oldest old
- Chapter 69 Common fractures in older adults
- Chapter 70 Management of common fractures in older adults
- Chapter 71 Secondary prevention of fragility fractures
- Chapter 72 Osteoarthritis
- Chapter 73 Low back pain in older adults
- Chapter 74 Vasculitides in older people
- Chapter 75 Management of common types of arthritis in older adults
- Chapter 76 Foot problems
- Chapter 77 Injuries in sports activities in older people
- Chapter 78 Orthogeriatrics
- Section 8 Infections in older adults: epidemiology, pathophysiology, diagnosis, and management
- Section 9 Cancer: epidemiology, pathophysiology, diagnosis, and management
- Section 10 Vascular diseases: epidemiology, pathophysiology, diagnosis, and management
- Section 11 Neurological disorders: epidemiology, pathophysiology, diagnosis, and management
- Section 12 Cognitive decline and dementia in older adults: epidemiology, pathophysiology, diagnosis, and management
- Section 13 Mental health of older adults
- Section 14 Management of common medical conditions: epidemiology, pathophysiology, diagnosis, and management
- Section 15 Palliative medicine and end-of-life care
- Section 16 Healthy ageing