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Osteoporosis in the oldest old: epidemiology, assessment, and management 

Osteoporosis in the oldest old: epidemiology, assessment, and management
Chapter:
Osteoporosis in the oldest old: epidemiology, assessment, and management
Author(s):

René Rizzoli

DOI:
10.1093/med/9780198701590.003.0068
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date: 18 August 2019

Osteoporosis and frailty greatly increase the risk of fracture. Hip fractures are the most serious osteoporotic fractures, with increased risk of mortality. In most countries, the majority are over 80 years old. Large rises on hip and other fragility fracture rates are predicted for much of South America and Asia in the coming decades. The survivors have a high risk of sustaining another major fracture and face deterioration in their quality of life and high risk of dependency. Optimal protein and calcium intakes, and vitamin D supplies, together with regular weight-bearing physical exercise are the cornerstones of fracture prevention. Evidence for antifracture efficacy of pharmacological interventions relies on randomized controlled trials in postmenopausal women between the ages of 50 and 80 years and the evidence of antiosteoporotic efficacy in the oldest old has come primarily from subgroup analyses.

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