Show Summary Details
Page of

Ischaemic heart disease 

Ischaemic heart disease
Chapter:
Ischaemic heart disease
Author(s):

Martina Rafanelli

, Francesco Orso

, and Niccolò Marchionni

DOI:
10.1093/med/9780198701590.003.0106
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2016. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 23 October 2019

Advancing age is associated with changes in vascular and cardiac properties that increase the likelihood of atherosclerosis, which is the basic pathophysiological mechanism in most of the clinical presentations of ischaemic heart disease (IHD). Recovery, once the tissue’s damage has occurred, is more difficult because of age-related changes in damage responsiveness. Clinical management of IHD in older people is complicated by atypical presentation that often makes the diagnosis challenging and causes treatment delay. The management of acute coronary syndromes (ACS) and stable coronary artery disease in this population should be driven by current clinical guidelines, even though older people are poorly represented in clinical trials. The choice of pharmacological therapy needs a careful balance between risks and benefits. Given the increase in morbidity and mortality in older patients with ACS, aggressive risk factor modification is vital for decreasing recurrent events.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.