Show Summary Details
Page of



Heather Baid

, Fiona Creed

, and Jessica Hargreaves

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2016. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 21 September 2019

The pathophysiology, management, and treatment of erythrocyte disorders, such as polycythaemia and sickle-cell anaemia, and leucocyte disorders, such as neutropenia and the various types of leukaemia, are explained. The causes and management of thrombocyte disorders, including thrombocytopenia, idiopathic thrombocytopenic purpura, thrombotic thrombocytopenic purpura, and heparin-induced thrombocytopenia syndrome are also described. There is a review of the pharmacology, indications, monitoring, and reversal procedures for a range of medications that are used for anticoagulant therapy, including heparin, warfarin, factor Xa inhibitors, clopidogrel, thrombolytic agents, and direct thrombin inhibitors. Specific clotting disorders are considered, including disseminated intravascular coagulation and haemophilia. The final section focuses on the transfusion of blood components, including packed red blood cells, platelets, fresh frozen plasma, and cryoprecipitate. The complications and hazards of transfusion are also summarized.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.