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Investigation for possible MS 

Investigation for possible MS
Investigation for possible MS

John Zajicek

, Jennifer Freeman

, and Bernadette Porter

Page of

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date: 18 January 2020

Introduction and initial tests 96

Magnetic resonance imaging (MRI) in MS 98

Lumbar puncture and cerebrospinal fluid (CSF) analysis 108

Evoked potentials 110

The most important aspect of achieving a diagnosis for any neurological condition is to take a good history. When a person presents with definite episodes of neurological dysfunction, attributable to well-recognized MS syndromes, with evidence from a clear history and supported by clinical examination, there is a good argument for making a clinical diagnosis and not doing any tests at all. However, these days most people expect a scan, and it will help to determine prognosis, treatment options, and assist the patient in understanding their condition. The issue then remains as to how far one should go in trying to exclude other potentially rare causes for similar conditions. Most people would perform the tests in ...

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