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Postural orthostatic tachycardia syndrome 

Postural orthostatic tachycardia syndrome
Postural orthostatic tachycardia syndrome

Phillip A. Low

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date: 18 October 2021

Postural orthostatic tachycardia syndrome (POTS) is a syndrome comprising specific symptoms and signs. Symptoms are those of cerebral hypoperfusion and/or autonomic overactivity, which develop while the subject is standing but are relieved by recumbency. Symptoms of hypoperfusion include light-headedness, dizziness, diminished concentration, and syncope; those of autonomic overaction include palpitations, tremulousness, nausea, and syncope. The essential finding is a heart rate (HR) increment of 30 beats/minute or greater within 5 minutes of standing up or on head-up tilt (HUT). Some investigators require an absolute orthostatic HR greater than 120 beats/minute and/or standing plasma norepinephrine ≥600 pg/ml....

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