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- Chapter 1 Introduction: The Origins and Rise of BenzodiazepinesMichael M. Miller and John F. Peppin
- Chapter 2 The Evolution of Benzodiazepine Receptor Agonists: Developments in Pharmacology and ToxicologyJamie L. Hansen and Timothy J. Atkinson
- Chapter 3 Benzodiazepine Therapy: The Good, the Bad, and the UglyJeffrey Guina, Brian Merrill, and Jo Ann LeQuang
- Chapter 4 Use of Benzodiazepines and Z-Drugs in the Geriatric PopulationJan M. Kitzen
- Chapter 5 The Central Benzodiazepine ReceptorMichael H. Ossipov
- Chapter 6 Benzodiazepine Receptors in the PeripheryRobert B. Raffa
- Chapter 7 Drug Withdrawal: A Modern Motivational View and Neurobiological SubstratesGeorge F. Koob
- Chapter 8 Benzodiazepine Withdrawal: Clinical AspectsSteven L. Wright
- Chapter 9 Benzodiazepines and Pain Management John F. Peppin and Steven L. Wright
- Chapter 10 The Regulatory History of Benzodiazepines in the Age of the Dark Web and Other ThreatsJohn J. Coleman
- Chapter 11 Benzodiazepines Today and Tomorrow: What We Know and Don’t Know About ThemJohn J. Coleman
- Chapter 12 In Search of Benzodiazepine GuidelinesJo Ann LeQuang
- ConclusionJohn F. Peppin, Joseph V. Pergolizzi Jr., Robert B. Raffa, and Steven L. Wright