- Contributors
- 1 Framing Definitions
- 2 Leveraging Convergence Science to Address Global Mental Health Challenges
- 3 On the Road to Convergence Research
- 4 Convergence and the Changing Nature of Innovation
- 5 Developing Convergence Neuroscience as a Model
- 6 Establishing Transdisciplinarity Within a University
- 7 The OECD Approach to Responsible Innovation
- 8 The Therapeutic Centaur
- 9 Update on the War on Mental Illness
- 10 Promoting Early Child Development
- 11 Artificial Intelligence in Mental Health
- 12 Precision Mental Health
- 13 Emerging Role for Technology in Positive Psychiatry Interventions
- 14 A Social, Behavioral, and Implementation Science Perspective on Convergence Mental Health
- 15 Convergence Mental Health Across the Life Span
- 16 Convergence Neuroscience of Meditative Mind–Body Therapies for Mental Health
- 17 The Use of Bioinformatics and Big Data for the In Silico Study of Psychiatric Disorders
- 18 Converging Technologies Between the Space Mars Mission and Earth Global Mental Health
- 19 Innovation Diplomacy in the Clinical Neurosciences
- 20 Toward Multi-Omic–Informed Psychotropic Prescribing
- 21 Biobehavioral Sensing for Objective Evaluation of OCD Patients
- 22 An Introduction to Antidepressant Pharmacomicrobiomics and Implications in Depression
- 23 Blockchain for Convergence Science in Mental Health
- 24 Global Mental Health and Technology
- 25 Digital Health Entrepreneurship
- 26 Stanford’s Brainstorm Lab for Mental Health Innovation
- 27 Innovating Dementia Care Through Convergence Science in Brain Health
- 28 NODE.Health Algorithm to Support Digital Mental Health Validation
- 29 Key Considerations for Developing Digital Health Accelerators
- 30 Screening for Convergent Practitioners in Health Research and Innovation
- 31 The Minds Behind the Technology
- 32 Consumer Participation in Personalized Psychiatry
- 33 Collaborative Research and Investment to Secure “Healthy Brains for All”
- 34 Unconventional Approaches to Investing in Mental Health Technology
- 35 Convergence Mental Health
- 36 Trans-Sectoral Neuroscience Innovation for the 21st Century
- 37 A Roadmap Toward Convergence Mental Health
- Index
(p. 303) Toward Multi-Omic–Informed Psychotropic Prescribing
- Chapter:
- (p. 303) Toward Multi-Omic–Informed Psychotropic Prescribing
- Author(s):
Abdullah Al Maruf
, and Chad Bousman
- DOI:
- 10.1093/med/9780197506271.003.0020
Matching individuals to tolerable and efficacious pharmacotherapies in mental health has proven challenging. As such, efforts to personalize psychotropic prescribing in mental health has received considerable attention over the past decade. This attention has been fueled by technological advances in genomics, specifically, pharmacogenomics, and, more recently, epigenomics, transcriptomics, proteomics, and metabolomics that have facilitated the identification of clinically useful biological markers to guide medication selection and dosing. The convergence of these omic technologies is arguably the future of personalized psychotropic prescribing. This chapter provides an overview of the current genomic, epigenomic, transcriptomic, proteomic, and metabolomic knowledgebase as it relates to psychotropic drug response in an effort to identify promising linkages between and facilitate convergence across these approaches to guide safe and effective pharmacotherapy relevant to psychiatry.
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- Contributors
- 1 Framing Definitions
- 2 Leveraging Convergence Science to Address Global Mental Health Challenges
- 3 On the Road to Convergence Research
- 4 Convergence and the Changing Nature of Innovation
- 5 Developing Convergence Neuroscience as a Model
- 6 Establishing Transdisciplinarity Within a University
- 7 The OECD Approach to Responsible Innovation
- 8 The Therapeutic Centaur
- 9 Update on the War on Mental Illness
- 10 Promoting Early Child Development
- 11 Artificial Intelligence in Mental Health
- 12 Precision Mental Health
- 13 Emerging Role for Technology in Positive Psychiatry Interventions
- 14 A Social, Behavioral, and Implementation Science Perspective on Convergence Mental Health
- 15 Convergence Mental Health Across the Life Span
- 16 Convergence Neuroscience of Meditative Mind–Body Therapies for Mental Health
- 17 The Use of Bioinformatics and Big Data for the In Silico Study of Psychiatric Disorders
- 18 Converging Technologies Between the Space Mars Mission and Earth Global Mental Health
- 19 Innovation Diplomacy in the Clinical Neurosciences
- 20 Toward Multi-Omic–Informed Psychotropic Prescribing
- 21 Biobehavioral Sensing for Objective Evaluation of OCD Patients
- 22 An Introduction to Antidepressant Pharmacomicrobiomics and Implications in Depression
- 23 Blockchain for Convergence Science in Mental Health
- 24 Global Mental Health and Technology
- 25 Digital Health Entrepreneurship
- 26 Stanford’s Brainstorm Lab for Mental Health Innovation
- 27 Innovating Dementia Care Through Convergence Science in Brain Health
- 28 NODE.Health Algorithm to Support Digital Mental Health Validation
- 29 Key Considerations for Developing Digital Health Accelerators
- 30 Screening for Convergent Practitioners in Health Research and Innovation
- 31 The Minds Behind the Technology
- 32 Consumer Participation in Personalized Psychiatry
- 33 Collaborative Research and Investment to Secure “Healthy Brains for All”
- 34 Unconventional Approaches to Investing in Mental Health Technology
- 35 Convergence Mental Health
- 36 Trans-Sectoral Neuroscience Innovation for the 21st Century
- 37 A Roadmap Toward Convergence Mental Health
- Index
