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Magnetic Resonance Imaging 

Magnetic Resonance Imaging
Chapter:
Magnetic Resonance Imaging
Author(s):

Terry L. Jernigan

, Sarah L. Archibald

, and Christine Fennema-Notestine

DOI:
10.1093/med/9780195399349.003.0057
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date: 26 May 2019

This chapter reviews reports of structural and biological changes in the brains of individuals living with HIV infection. This information has come almost exclusively from magnetic resonance imaging, which is the most sensitive method available for characterizing structural damage to brain tissue in vivo. Because the incidence of focal opportunistic infections of the central nervous system has declined with the introduction of antiretroviral therapies (ART), this chapter focuses on individuals with no evidence of such infections. Thus, this is a review of imaging findings associated with chronic HIV-infection per se. This information has become increasingly important as more potent ARTs reduce viral replication, improve immune function, and increase longevity in HIV+ individuals.

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