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Murine Models for NeuroAIDS 

Murine Models for NeuroAIDS
Chapter:
Murine Models for NeuroAIDS
Author(s):

Larisa Y. Poluektova

DOI:
10.1093/med/9780195399349.003.0029
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date: 17 June 2019

Among the animal models for HIV disease, non-human primates infected with SIV or chimeric SIV/HIV viruses best mimic human disease. However, limitations in cost and availability have limited the extent of research with these animals. For this and other reasons, mouse models, particularly those using immunodeficient and transgenic mice, have played an essential role. This chapter reviews these two important types of murine models.

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