- In Memoriam
- Foreword to the First Edition
- Preface to the Second Edition
- Preface to the First Edition
- Contributors
- IBiological Bases of Pediatric Psychopharmacology
- 1 Overview of Brain Development
- 2 Synaptic Function and Biochemical Neuroanatomy
- 3 Developmental Principles of Pharmacokinetics
- 4 Cytochrome P450-Mediated Drug Interactions
- II Somatic Interventions
- III Assessment and Treatment
- IV Epidemiological, Research, and Methodological Considerations
- 49 Pediatric Psychopharmacoepidemiology: Who Is Prescribing? And For Whom, How, and Why?
- 50 Clinical Trials Methodology and Designs
- 51 Regulatory Issues
- 52 Ethical Issues in Pediatric Psychopharmacology
- 53 Conflict of Interest
- 54 International Patterns of Pediatric Medication for Emotional and Behavioral Disorders
- Appendix: Psychopharmacology at a Glance
- Disclosures of Financial Interests
- Index
(p. 50) Cytochrome P450-Mediated Drug Interactions
- Chapter:
- (p. 50) Cytochrome P450-Mediated Drug Interactions
- Author(s):
Jessica R. Oesterheld
and Miia Turpeinen
- DOI:
- 10.1093/med/9780195398212.003.0004
Chapter 4 outlines an approach that child psychiatrists can use to develop a proactive stance toward possible interactions with drugs they prescribe, and includes vignettes to highlight clinically relevant aspects of CYP-based drug interactions, and focuses on central serotonin syndrome (CSS) as an example of the intertwining of CYP-based pharmacokinetic and pharmacodynamics factors that may occur during the use of psychotherapeutics in children.
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- In Memoriam
- Foreword to the First Edition
- Preface to the Second Edition
- Preface to the First Edition
- Contributors
- IBiological Bases of Pediatric Psychopharmacology
- 1 Overview of Brain Development
- 2 Synaptic Function and Biochemical Neuroanatomy
- 3 Developmental Principles of Pharmacokinetics
- 4 Cytochrome P450-Mediated Drug Interactions
- II Somatic Interventions
- III Assessment and Treatment
- IV Epidemiological, Research, and Methodological Considerations
- 49 Pediatric Psychopharmacoepidemiology: Who Is Prescribing? And For Whom, How, and Why?
- 50 Clinical Trials Methodology and Designs
- 51 Regulatory Issues
- 52 Ethical Issues in Pediatric Psychopharmacology
- 53 Conflict of Interest
- 54 International Patterns of Pediatric Medication for Emotional and Behavioral Disorders
- Appendix: Psychopharmacology at a Glance
- Disclosures of Financial Interests
- Index