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- In Memoriam
- Foreword to the First Edition
- Preface to the Second Edition
- Preface to the First Edition
- Contributors
- IBiological Bases of Pediatric Psychopharmacology
- 1 Overview of Brain Development
- 2 Synaptic Function and Biochemical Neuroanatomy
- 3 Developmental Principles of Pharmacokinetics
- 4 Cytochrome P450-Mediated Drug Interactions
- II Somatic Interventions
- III Assessment and Treatment
- IV Epidemiological, Research, and Methodological Considerations
- 49 Pediatric Psychopharmacoepidemiology: Who Is Prescribing? And For Whom, How, and Why?
- 50 Clinical Trials Methodology and Designs
- 51 Regulatory Issues
- 52 Ethical Issues in Pediatric Psychopharmacology
- 53 Conflict of Interest
- 54 International Patterns of Pediatric Medication for Emotional and Behavioral Disorders
- Appendix: Psychopharmacology at a Glance
- Disclosures of Financial Interests
- Index
(p. 38) Developmental Principles of Pharmacokinetics
(p. 38)
Developmental Principles of Pharmacokinetics
- Chapter:
- (p. 38) Developmental Principles of Pharmacokinetics
- Author(s):
Alexander A. Vinks
, Shannon N. Saldaña
, and Philip D. Walson
- DOI:
- 10.1093/med/9780195398212.003.0003
Chapter 3 discusses the protocols to do with early studies in children, with emphasis on pharmacokinetics and pharmacodynamic behaviors that are important to understand and predict developmental differences in drug response.
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- In Memoriam
- Foreword to the First Edition
- Preface to the Second Edition
- Preface to the First Edition
- Contributors
- IBiological Bases of Pediatric Psychopharmacology
- 1 Overview of Brain Development
- 2 Synaptic Function and Biochemical Neuroanatomy
- 3 Developmental Principles of Pharmacokinetics
- 4 Cytochrome P450-Mediated Drug Interactions
- II Somatic Interventions
- III Assessment and Treatment
- IV Epidemiological, Research, and Methodological Considerations
- 49 Pediatric Psychopharmacoepidemiology: Who Is Prescribing? And For Whom, How, and Why?
- 50 Clinical Trials Methodology and Designs
- 51 Regulatory Issues
- 52 Ethical Issues in Pediatric Psychopharmacology
- 53 Conflict of Interest
- 54 International Patterns of Pediatric Medication for Emotional and Behavioral Disorders
- Appendix: Psychopharmacology at a Glance
- Disclosures of Financial Interests
- Index
