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Endolymphatic Hydrops (Meniere’s Syndrome) 

Endolymphatic Hydrops (Meniere’s Syndrome)
Chapter:
Endolymphatic Hydrops (Meniere’s Syndrome)
Author(s):

Robert W. Baloh

, Vicente Honrubia

, and Kevin A. Kerber

DOI:
10.1093/med/9780195387834.003.0011
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date: 21 April 2021

The clinical profile of Meniere’s disease evolved over the years from a nonspecific description of just about any combination of hearing loss and vertigo to a characteristic clinical triad of fluctuating hearing loss, tinnitus, and vertigo. Once a characteristic pathology—endolymphatic hydrops—was discovered in the late 1930s,3,4 the next question was whether patients with the typical clinical profile consistently showed this pathology. As more and more pathological specimens have been reported, the answer to this question is, usually but not always.58 Complicating matters further, endolymphatic hydrops can be found in ears from patients without the typical symptoms of Meniere’s disease and, occasionally, even in patients without ear symptoms.810 Furthermore, it has become apparent that Meniere’s syndrome and the characteristic inner ear pathology can be produced by several different etiologies, including infections (syphilitic, bacterial, and viral) and after traumatic and metabolic injuries to the inner ear.

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