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Leslie L. Iversen

, Susan D. Iversen

, Floyd E. Bloom

, and Robert H. Roth

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date: 06 August 2021

Of all the psychoactive drugs, the psychedelics are perhaps the strangest. These are chemicals that are capable of inducing profound changes in the state of consciousness, with altered perception and strange illusions. The drug state has been likened by some to a mystical experience but viewed by others as a form of psychosis—hence the alternative term psychotomimetic to describe these drugs. This is a diverse group of drugs whose effects are not all identical, but to be included in this class, the following criteria should be fulfilled: 1) The main effect is on thought, perception, and mood. 2) There is only minimal intellectual or memory impairment. 3) Stupor or psychostimulation is not an integral part of the drug action. 4) Autonomic side effects are not disabling. 5) There is little or no dependence liability.

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