Show Summary Details
Page of

From Toddlers to Adults: The Changing Landscape of the Brain in Autism 

From Toddlers to Adults: The Changing Landscape of the Brain in Autism
From Toddlers to Adults: The Changing Landscape of the Brain in Autism

Eric Courchesne

, Sara Jane Webb

, and Cynthia M. Schumann

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2020. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 12 July 2020

Recent research in early brain development in autism has led to the theory that autism involves early brain overgrowth followed by arrested growth and potential degeneration. If the early brain overgrowth theory of autism is valid, then it would provide a central organizing principle for a host of research into genetic and nongenetic causes, avenues for treatment, animal models, and early identification. This chapter reviews the head circumference and MRI evidence relevant to this theory, and highlights areas of evidence that remain to be gathered to refine or refute it. It discusses new information from functional neuroimaging and postmortem studies that speak to this theory. It suggests future directions in research into the early developmental neuroanatomical bases of autism, including research that aims to define relationships between brain growth abnormality in autism spectrum disorders and clinical, treatment, and etiological factors.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.