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DWI in Cerebral Ischemia: The Early Days 

DWI in Cerebral Ischemia: The Early Days
Chapter:
DWI in Cerebral Ischemia: The Early Days
Author(s):

Michael E. Moseley

DOI:
10.1093/med/9780195369779.003.0046
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date: 27 January 2020

The early utility of diffusion-weighted MRI was focused on the assessment and depiction of experimental acute cerebral ischemia. This came about from refinements of the diffusion MR methods using large magnetic field gradients afforded by the key hardware advances in self-shielded gradient coils by the mid-1980s. The new gradients could dramatically increase the diffusion sensitivity of the MRIs, from which the apparent diffusion changes in ischemic brain become readily visualized. The history and personal recollections of these advances are presented in this chapter.

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