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Minor Anomalies/Normal Variations 

Minor Anomalies/Normal Variations
Chapter:
Minor Anomalies/Normal Variations
Author(s):

Lewis B. Holmes

DOI:
10.1093/med/9780195136029.003.0025
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date: 11 August 2020

This chapter covers minor anomalies and normal variations. Most infants with one or more minor physical features are healthy. The challenge for a busy clinician is to recognize the infant who is “dysmorphic” and could have a significant multiple anomaly syndrome. This chapter looks at the association of minor anomalies with major medical problems, and associations with major malformations, mental deficiency or illness, hyperactive behavior, autism, schizophrenia, low birth weight, stillbirth, twinning and malignancy. It also addresses the limitations of using minor anomalities in research studies before looking at specific minor physical features affecting the various parts of the body.

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