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Gestational diabetes 

Gestational diabetes
Gestational diabetes

Murray Enkin

, Marc J. N. C. Keirse

, James Neilson

, Caroline Crowther

, Lelia Duley

, Ellen Hodnett

, and Justus Hofmeyr

Page of

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date: 28 October 2020

“Chapter 11 discusses how gestational diabetes evolved from the earlier concept of prediabetes, which held that much of the pathology associated with overt diabetes develops before the appearance of insulin dependency. The glucose-tolerance test became the mainstay of this diagnosis, as it was believed to uncover a defect in glucose homeostasis that could only be demonstrated after a glucose challenge. It was not until 1973 that an attempt was made to link prediabetes (an abnormal glucosetolerance test in the absence of overt disease) to perinatal outcome. Although this link is remarkably tenuous, it gave rise to the concept of gestational diabetes as a disease entity, to be searched for and treated. Caregivers and women became anxious lest ‘gestational diabetes’ develop, and various forms of glucose-challenge screening were introduced and carried out to identify the condition. It also covers the risks of ‘gestational diabetes’, therapy in ‘gestational diabetes’, and the effects of glucose-tolerance testing.”

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