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Screening for pre-eclampsia 

Screening for pre-eclampsia
Chapter:
Screening for pre-eclampsia
Author(s):

Murray Enkin

, Marc J. N. C. Keirse

, James Neilson

, Caroline Crowther

, Lelia Duley

, Ellen Hodnett

, and Justus Hofmeyr

DOI:
10.1093/med/9780192631732.003.0010
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date: 18 August 2019

Chapter 10 discusses hypertensive disorders in pregnancy, which comprise at least two etiologically distinct entities. One is a disorder mainly, but not exclusively, of women having their first baby, which appears during the course of pregnancy and is reversed by delivery. This is referred to as ‘pregnancy-induced hypertension’, if there is hypertension alone, and as ‘preeclampsia’, if there is associated proteinuria. Since the causes of the hypertensive disorders of pregnancy are not fully understood, definition and diagnosis are usually based on the signs that are considered to be most characteristic: hypertension and proteinuria, which constitute secondary features of an underlying circulatory disorder, thought to originate in faulty implantation of the placenta. As signs they are nonspecific; they can be induced by pregnancy itself, as well as by a variety of conditions unrelated to, but coinciding with pregnancy. Hypertension and proteinuria are usually asymptomatic and must, therefore, be detected by screening. It also covers edema, biochemical and biophysical tests, and Doppler ultrasound.

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