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Stiff man syndromes: The stiff man (person) syndrome 

Stiff man syndromes: The stiff man (person) syndrome
Chapter:
Stiff man syndromes: The stiff man (person) syndrome
Author(s):

Ivan Donaldson

, C. David Marsden

, Susanne A. Schneider

, and Kailash P. Bhatia

DOI:
10.1093/med/9780192619112.003.1095
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date: 01 December 2021

The stiff man (stiff person) syndrome is a chronic disorder characterized by continuous, widespread, and often painful contraction of skeletal muscles, involving agonists and antagonists and accompanied by sustained motor unit activity on electromyography (EMG). These features are abolished by peripheral nerve blockade.

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