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Simple tics 

Simple tics
Simple tics

Ivan Donaldson

, C. David Marsden

, Susanne A. Schneider

, and Kailash P. Bhatia

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date: 03 July 2022

Simple tic, habit spasm, or transient tic disorder of childhood is a well-recognized and common condition, but there is surprisingly little medical information about this (Shapiro and Shapiro 1986).

It is not associated with known anatomical pathology, neurotransmitter abnormality, pathophysiology, or cause. Kurlan ( 1994) hypothesized that it results from the development of normal synaptogenesis within the basal ganglia. It has been suggested that in some children the onset of tics may be associated with betahaemolytic streptococcal infection and the development of antibodies, which react with the D2 dopamine receptor. It seems unlikely that this is responsible for the majority of cases of this very frequent childhood movement disorder.

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