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Parathyroid Diseases and Renal Osteodystrophy 

Parathyroid Diseases and Renal Osteodystrophy
Chapter:
Parathyroid Diseases and Renal Osteodystrophy
Author(s):

Kevin B. Hoover

DOI:
10.1093/med/9780190938178.003.0082
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date: 09 December 2021

Chapter 82 discusses parathyroid diseases and renal osteodystrophy. Parathyroid disease disrupts calcium homeostasis with systemic effects including abnormal bone metabolism. Secondary hyperparathyroidism, caused by chronic kidney disease, is the most common parathyroid disease. Diagnosis is primarily based on serum calcium, phosphate, and parathyroid hormone levels rather than imaging. However, there are characteristic findings that may suggest the diagnosis of parathyroid disease. Resorption of bone is the most important radiographic finding in primary hyperparathyroidism. Increase in bone density is the most specific radiographic and DXA finding in hypoparathyroidism. Treatment is dependent on disease, for example, parathyroidectomy is standard treatment for hyperparathyroidism, whereas hypoparathyroidism is treated with calcium supplementation.

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