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Lymphoproliferative and Myeloproliferative Disorders 

Lymphoproliferative and Myeloproliferative Disorders
Lymphoproliferative and Myeloproliferative Disorders

Kevin B. Hoover

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date: 09 December 2021

Chapter 78 discusses lymphoproliferative and myeloproliferative disorders, which are a disparate group of premalignant and malignant neoplasms originating in or metastasizing to the bone marrow. Included in this group of disorders is primary myelofibrosis, systemic mastocytosis, leukemia, and lymphoma. Because these tend to involve the marrow more often than the cortex, they are best detected by MRI and nuclear imaging techniques, including FDG-PET and CT. Distinguishing the disorders by imaging is often difficult because of the overlap in imaging findings. Imaging is beneficial to guide biopsy, which is crucial in diagnosis, and to assess treatment response.

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