Show Summary Details
Page of

The Gut Microbiome in Integrative Gastroenterology 

The Gut Microbiome in Integrative Gastroenterology
The Gut Microbiome in Integrative Gastroenterology

Gerard E. Mullin

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2021. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 24 June 2021

The gut microbiome consists of trillions of bacteria that play an essential role in human metabolism. Environmental factors play a role in the development of the gut microbiome. Hygiene, antibiotic usage, urbanization, mode of birth, breast-feeding, and family size influence the development of the gut microbiota in early life. Distortion in the gut microbial ecology has been linked to the pathophysiology of many diseases via disruption of the gut barrier lining, promoting local and systemic inflammation, and by the systemic dissemination of bacteria-derived byproducts, and other luminal antigens that set into motion a cascade of deleterious events. Manipulation of the gut flora through diet, prebiotics and probiotics, antibiotics, and fecal transplantation has the potential to influence digestive disease health outcomes.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.