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Colorectal Cancer 

Colorectal Cancer
Chapter:
Colorectal Cancer
Author(s):

George Kunnackal John

, and Mohammed Razvi

DOI:
10.1093/med/9780190933043.003.0019
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date: 19 April 2021

Colorectal cancer (CRC) is a leading cause of cancer-related mortality globally. However, the adoption of a healthier lifestyle, including modifications in diet, physical activity, and regular screening can drastically reduce the risk for CRC. Major risk factors for CRC include lack of a balanced diet, high red meat intake, physical inactivity, alcohol, and smoking. There is widespread geographic variation in the rates of CRC across the world, reflecting differences in exposure to these risk factors and the influence of protective factors in these regions. In this chapter, we summarize the epidemiology, pathogenesis, and risk factors, and focus on the prevention of CRC through an integrative approach.

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