Show Summary Details
Page of

Neurocognitive Disorders 

Neurocognitive Disorders
Chapter:
Neurocognitive Disorders
Author(s):

Thomas Gossard

, and Erik K. St. Louis

DOI:
10.1093/med/9780190929671.003.0025
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2021. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 08 March 2021

Recent evidence for a strong bidirectional relationship between sleep and neurocognitive disorders has emerged. A key function of sleep in brain health is drainage of metabolites and toxins such as beta-amyloid that accumulate with continued wakefulness, making insufficient sleep, and sleep disorders possible contributors toward development of neurodegeneration. Sleep disturbances are frequent in patients with dementia and neurocognitive disorders, including poor sleep efficiency and architecture, sleep disordered breathing, sleep-related limb movements, and parasomnias. This chapter highlights current DSM-5 classifications for the major and mild neurocognitive disorders, including Alzheimer’s and Lewy body diseases and the related prodromal states of amnestic and nonamnestic mild cognitive impairment; less common neurodegenerative dementias are also reviewed. Diagnostic and therapeutic approaches to key sleep comorbidities in patients with neurocognitive disorders including insomnia, hypersomnia, sleep-disordered breathing, nocturnal movements, and parasomnias are also discussed.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.